The German side are second-bottom of the table on their return to the Bundesliga and have won only once all season.
“After achieving promotion last season, our goal for the new campaign was to remain in the Bundesliga. Until recently we were convinced that we could turn things around with the current coaching setup, but from our point of view, we’ve now reached a point in time that we have to make a change,” sporting director Rouven Schroder said.
“In the remaining five league games ahead of longer than usual World Cup break, we need to pick up points to put us in the best possible position for what is a hugely important second half of the season for the club.”